Pathophysiology of asthma: a present-day outlook
Fisiopatología del asma: una mirada actual
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Asthma is a constantly evolving, heterogeneous, and complex disease. We now talk about molecular phenotypes that have slowly changed its diagnostic and therapeutic approach; these phenotypes identify new targets for pharmacologic tools currently under development.
There are host factors that predispose patients to develop the disease, as well as environmental factors and clinical situations that favor the appearance or worsening of asthma.
We describe the immunological cascade with the individual events that lead to the development of asthma, and the characteristics of the immune response in severe asthma, plus the remodeling of the airway.
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