Stops during the six-minute walk test and their correlation with new measurements of the test in patients with obstructive pulmonary disease

Paradas durante la caminata de 6 minutos y su correlación con nuevas mediciones de la prueba en pacientes con enfermedad pulmonar obstructiva crónica

Published 2016-07-04

Open | Download
PDF (Spanish) FLIP
Issue
Vol. 27 No. 2 (2015)
Section
Research article
How to Cite
Stops during the six-minute walk test and their correlation with new measurements of the test in patients with obstructive pulmonary disease.
rev. colomb. neumol. [Internet]. 2016 Jul. 4 [cited 2024 Nov. 21];27(2). Disponible en: https://doi.org/10.30789/rcneumologia.v27.n2.2015.26
DOI

https://doi.org/10.30789/rcneumologia.v27.n2.2015.26
Dimensions
PlumX
license

Ninguna publicación, nacional o extranjera, podrá reproducir ni traducir sus artículos ni sus resúmenes sin previa autorización escrita del editor; sin embargo  los usuarios pueden descargar la información contenida en ella, pero deben darle atribución o reconocimiento de propiedad intelectual, deben usarlo tal como está, sin derivación alguna.

María José Fernández Sánchez
Departamento de Fisiología y Farmacología, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia; Departamento de Medicina Interna, Hospital Universitario San Ignacio, Bogotá, D.C., Colombia. Unidad de Neumología, Hospital Universitario San Ignacio, Bogotá, D.C., Colombia.
    Milena García
    Unidad de Neumología, Hospital Universitario San Ignacio, Bogotá, D.C., Colombia.
      Ximena Correa Ríos
      Unidad de Neumología, Hospital Universitario San Ignacio, Bogotá, D.C., Colombia
        Alejandra Cañas
        Unidad de Neumología, Hospital Universitario San Ignacio, Bogotá, D.C., Colombia
          Javier Iván Lasso
          Unidad de Neumología, Hospital Universitario San Ignacio, Bogotá, D.C., Colombia
            Show authors biography

            Theoretical frame: it has been reported that involuntary stops during the six-minute walk test are associated with increased mortality in patients with chronic obstructive pulmonary disease. However, the relationship between the stops and other determinations of the six-minute walk test, such as speed, work, the distance-saturation product, and exercise-induced desaturation, has not yet been established.

            Objectives: to determine the correlation between involuntary stops and clinical variables gathered routinely in the six-minute walk test, as well as the new determinations derived from the test, in patients with chronic obstructive pulmonary disease.

            Materials and methods: an observational, analytic, retrospective study was carried out, in which the reports of six-minute walk tests from 129 subjects with chronic obstructive pulmonary disease were reviewed. The determinations derived from the test were compared between the patients who had stops and those who hadn’t; correlations between them were made, and predictors of stops were identified by logistic regression anaylysis.

            Results: 30 patients had involuntary stops during the test; in this group, it was observed in the end that scores of dyspnea and fatigue, as well as heart rate, respiratory rate, and final systolic arterial blood pressure were significantly higher than those found in the group that did not have stops, while arterial blood oxygen saturation was significantly lower (p<0,001); the new variables derived: distance, speed, work, and the distance-saturation produc were lower (p<0,001) in the subjects who stopped; a good correlation with them was found. On regression analysis, the variables that remained significant for the presence of stops were: final saturation, distance walked, speed, work,DDR, and distance-saturation product.

            Conclusions: in patients with stable chronic obstructive pulmonary disease who undergo the six-minute walk test, stops are associated with less distance walked, work, DSP, and saturation at the end of the test. Calculation of these new variables, together with registration of stops during the six-minute walk test, might refine the prognostic capability of the test in patients with chronic obstructive pulmonary disease.

            Article visits 1847 | PDF visits 919

            Downloads

            Download data is not yet available.
            1. Burney PG, Patel J, Newson R, Minelli C, Naghavi M. Global and regional trends in COPD mortality, 1990-2010. Eur Respir J. 2015;45:1239-47.
            2. Caballero A, Torres-Duque CA, Jaramillo C, Bolívar F, Sanabria F, Osorio P, et al. Prevalence of COPD in five Colombian cities situated at low, medium, and high altitude (PREPOCOL study). Chest. 2008;133:343-9.
            3. Londoño D, García M, Celis CA, Giraldo M et al. Guía de práctica clínica basada en la evidencia para la prevención, diagnóstico, tratamiento y seguimiento de la enfermedad pulmonar obstructiva crónica (EPOC) en población adulta. Acta Med Col. 2014;39(2-3S):5-48.
            4. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med. 2004;350:1005-12.
            5. de Torres JP, Casanova C, Marín JM, Pinto-Plata V, Divo M, Zulueta JJ, et al. Prognostic evaluation of COPD patients: GOLD 2011 versus BODE and the COPD comorbidity index COTE. Thorax. 2014;69:799-804.
            6. Faganello MM, Tanni SE, Sanchez FF, Pelegrino NR, Lucheta PA, Godoy I. BODE index and GOLD staging as predictors of 1-year exacerbation risk in chronic obstructive pulmonary disease. Am J Med Sci. 2010;339:10-4.
            7. Marchand E. The BODE index as a tool to predict survival in COPD lung transplant candidates. Eur Respir J. 2010;36:1494-5.
            8. Ramon MA, Gimeno-Santos E, Ferrer J, Balcells E, Rodríguez E, de Batlle J, et al; PAC-COPD Study Group. Hospital admissions and exercise capacity decline in patients with COPD. Eur Respir J. 2014;43:1018-27.
            9. Trzaska-Sobczak M, Brożek G, Farnik M, Pierzchała W. Evaluation of COPD progression based on spirometry and exercise capacity. Pneumonol Alergol Pol. 2013;81:288-93.
            10. Vogiatzis I, Zakynthinos S. Factors limiting exercise tolerance in chronic lung diseases. Compr Physiol. 2012;2:1779-817.
            11. Janaudis-Ferreira T, Beauchamp MK, Goldstein RS, Brooks D. How should we measure arm exercise capacity in patients with COPD? A systematic review. Chest. 2012;141:111-20.
            12. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166:111-7.
            13. Singh SJ, Puhan MA, Andrianopoulos V, Hernandes NA, Mitchell KE, Hill CJ, et al. An official systematic review of the European Respiratory Society/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease. Eur Respir J. 2014;44:1447-78.
            14. Holland AE, Spruit MA, Troosters T, Puhan MA, Pepin V, Saey D, et al. An official European Respiratory Society/Ame rican Thoracic Society technical standard: field walking tests in chronic respiratory disease. Eur Respir J. 2014;44:1428-46.
            15. Polkey MI, Spruit MA, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Study Investigators. Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. Am J Respir Crit Care Med. 2013;187:382-6.
            16. Chandra D, Wise RA, Kulkarni HS, Benzo RP, Criner G, Make B, et al; NETT Research Group. Optimizing the 6-min walk test as a measure of exercise capacity in COPD. Chest. 2012;142:1545-52.
            17. Andrianopoulos V, Wouters EF, Pinto-Plata VM, Vanfleteren LE, Bakke PS, Franssen FM, et al. Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study. Respir Med. 2015 Jun 25. [Epub ahead of print].
            18. Studenski S, Perera S, Patel K, et al. Gait speed and survival in older adults. J. Am Med Assoc. 2011;30:50-8.
            19. Ilgin D, Ozalevli S, Kilinc O, Sevinc C, Cimrin AH, Ucan ES. Gait speed as a functional capacity indicator in patients with chronic obstructive pulmonary disease. Ann Thorac Med. 2011;6:141-6.
            20. Chuang ML, Lin IF, Wasserman K. The body weight-walking distance product as related to lung function, anaerobic threshold and peak VO2 in COPD patients. Respir Med. 2001;95:618-26.
            21. Carter R, Holiday DB, Nwasuruba C, Stocks J, Grothues C, Tiep B. 6-minute walk work for assessment of functional capacity in patients with COPD. Chest. 2003;123:1408-15.
            22. Alhamad EH, Shaik SA, Idrees MM, Alanezi MO, Isnani AC. Outcome measures of the 6 minute walk test: relationships with physiologic and computed tomography findings in patients with sarcoidosis. BMC Pulm Med. 2010;10:42.
            23. Lettieri CJ, Nathan SD, Browning RF, Barnett SD, Ahmad S, Shorr AF. The distance-saturation product predicts mortality in idiopathic pulmonary fibrosis. Respir Med. 2006;100:1734-41.
            24. Takigawa N, Tada A, Soda R, Date H, Yamashita M, Endo S, et al. Distance and oxygen desaturation in 6-min walk test predict prognosis in COPD patients. Respir Med. 2007;101:561-7.
            25. Casanova C, Cote C, Marin JM, Pinto-Plata V, de Torres JP, Aguirre-Jaime A, Vassaux C, Celli BR. and oxygen desaturation during the 6-min walk test as predictors of long-term mortality in patients with COPD. Chest. 2008;134:746-52.
            26. Wong R, Sibley KM, Hudani M, Roeland S, Visconti M, Balsano J, Hill K, Brooks D. characteristics of people with chronic lung disease who rest during the six-minute walk test. Arch Phys Med Rehabil. 2010;91:1765-9.
            27. Valero G, Bracciale P, Valerio F. Metabolic Requierements during six minutes walking tests in patients affected by chronic obstructive pulmonary disease in different stages. Open J Respir Dis. 2012;2:83-90.

            Information

            Journal history

            Keywords

            QR code

            Funding

            Support + Info: Here

             

             

            Directories and indexes

            Google Scholar profile

            Most read in the last 30 days

            Current Issue

            Sistema OJS 3.4.0.7 - Metabiblioteca |