Skip to main navigation menu Skip to main content Skip to site footer

Bronchial thermoplasty

Termoplastia bronquial




Section
Topics review

How to Cite
Bronchial thermoplasty.
rev. colomb. neumol. [Internet]. 2016 May 26 [cited 2024 Dec. 22];27(1). Disponible en: https://doi.org/10.30789/rcneumologia.v27.n1.2015.16

Dimensions
PlumX
license

Ninguna publicación, nacional o extranjera, podrá reproducir ni traducir sus artículos ni sus resúmenes sin previa autorización escrita del editor; sin embargo  los usuarios pueden descargar la información contenida en ella, pero deben darle atribución o reconocimiento de propiedad intelectual, deben usarlo tal como está, sin derivación alguna.

Olivia Sánchez Cabral
    Sebastián Fernández-Bussy

      Olivia Sánchez Cabral,

      Neumología y Broncoscopia, Instituto Nacional de Enfermedades Respiratorias (INER), Ciudad de México, México.

      Sebastián Fernández-Bussy,

      Director de Neumología Intervencionista, Clínica Alemana de Santiago, Chile.

      Asthma is a disease of the airways that is characterized by chronic inflammation, bronchial hyperreactivity, and variable airflow obstruction, triggered y a variety of stimuli, including, among others, allergic and infectious conditions. Bronchial thermoplasty is an innovative treatment carried out by applying radiofrequency energy to the proximal airways, in order to perform selective ablation of peribronchial muscle. It is the first non-pharmacologic interventional therapy approved by the Food and Drug Administration for severe asthma. Since it is a device-based therapy, its overall risk-benefit evaluation is different from that of pharmacologic products; aspects concerning safety, statutory requirements, study design, and assessment of the magnitude of its effects can be different. The mechanisms of action and the type of patients who could benefit from bronchial thermoplasty are the most important challenges for the future.

      Article visits 1055 | PDF visits 1883


      Downloads

      Download data is not yet available.
      1. FDA approves new device for adults with severe and persistent asthma. US Food and Drug Administration website. Disponible en: http://www. fda.gov/NewsEvents/Newsroom/
      2. PressAnnouncements/ ucm209909.htm. April 27, 2010. [Acceso 10 Apr 2014].
      3. Ebina M, Takahashi T, Chiba T, Motomiya M. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma: a 3-D morphometric study. Am Rev Respir
      4. Dis. 1993;148:720–6.
      5. Mayse ML, Laviolette M, Rubin AS. Clinical pearls for bronchial thermoplasty. J Bronchol. 2007; 14:115-23.
      6. Cox PG, Miller J, Mitzner W, Leff AR. Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: preliminary investigations. Eur Resp J. 2004;24:659-63.
      7. Jeffery PK. Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med. 2001;164:S28-38.
      8. Brown RH, Wizeman W, Danek C, Mitzner W. In vivo evaluation of the effectiveness of bronchial thermoplasty with computed tomography. J Appl Physiol. 2005;98:1603–6.
      9. Dyrda P, Tazzeo T, DoHarris L, Nilius B, Roman HN, Lauzon AM, Aziz T, Lukic D, Janssen LJ. Acute response of airway muscle to extreme temperature includes disruption of actin-myosin interaction. Am J Respir Cell Mol Biol. 2011;44:213–22.
      10. Cox G, Miller JD, McWilliams A, Fitzgerald JM, Lam S. Bronchial thermoplasty for asthma. Am J Respir Crit Care Med. 2006;173:965–9.
      11. Global Initiative for Asthma: Global Strategy for Asthma Management and Prevention. Revised December 2011. Disponible en: http://www.ginasthma.com/Guidelineitem.asp?l1=2&l2=1&intId=60
      12. Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, et al. International ERS/ATS guidelines on definition,evaluation and treatment of severe asthma. Eur Respir J.
      13. ;43:343-73.
      14. Miller JD, Cox G, Vincic L, Lombard CM, Loomas BE, Danek CJ. A prospective feasibility study of bronchial thermoplasty in the human airway. Chest. 2005;127:1999–2006.
      15. Wahidi MM, Kraft M. Bronchial thermoplasty for severe asthma.Am J Respir Crit Care Med. 2012 Apr 1;185:709-14.
      16. Pavord ID, Cox G, Thomson NC, Rubin AS, Corris PA, Niven RM, et al. Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med. 2007;176:1185–91.
      17. Cox G, Thomson NC, Rubin AS, Niven RM, Corris PA, Siersted HC, et al. Asthma control during the year after Fiterman J, De Andrade Lima M, et al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized,
      18. double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med. 2010; 181:116-24.
      19. Castro M, Rubin A, Laviolette M, Hanania NA, Armstrong B, Cox G; AIR2 Trial Study Group. Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma. Ann Allergy Asthma Immunol. 2011;107:65–70.
      20. Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa e Silva JR, Shah PL, et al. Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol. 2013;132:1295-302.
      21. Pavord ID, Thomson NC, Niven RM, Corris PA, Chung KF, Cox G, et al. Research in Severe Asthma Trial Study Group. Safety of bronchial thermoplasty in patients with severe refractory asthma. Ann Allergy Asthma Immunol. 2013;111:402–7.
      22. Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa e Silva JR, Shah PL, et al. Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma.J Allergy Clin Immunol. 2013;132:1295–302.
      23. Torrego A, Sola I, Muñoz A. Bronchial thermoplasty for moderate or severe persistent asthma in adults. Cochrane Database Syst Rev. 2014.
      Sistema OJS 3.4.0.7 - Metabiblioteca |