Neumonías adquiridas en la comunidad en adultos: Un estudio etiológico prospectivo con énfasis en el diagnóstico
Neumonías adquiridas en la comunidad en adultos: Un estudio etiológico prospectivo con énfasis en el diagnóstico
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Ninguna publicación, nacional o extranjera, podrá reproducir ni traducir sus artículos ni sus resúmenes sin previa autorización escrita del editor; sin embargo los usuarios pueden descargar la información contenida en ella, pero deben darle atribución o reconocimiento de propiedad intelectual, deben usarlo tal como está, sin derivación alguna.
Show authors biography
Objectives: To define prospective/y in adults the etiology of acquired pneumonia in the community (NAC) in three hospitals of the city of Medellin.
Materials and methods: The entrance was carried out with clinical diagnosis of NAC and compatible thorax x-ray. Sample of blood was obtained for blood count, sedimentation and protein C it reactivates (PCR), 2-3 blood culture and serum for antibodies antim ycoplasm, anti-legionella and anti-Chlamydia pneumoniae. Breathing sample was obtained for Gramand /egione/la cultivation and other conventional pathogenics.
Results: 76 patients were studied, 37 women, average 46. 6± 17 years. The symptoms and more frequent signs were cough, fever, taquipnea and stertors. The Rx showed alveolar pattern in 73.3%, interstitial in 10.5% and mixed in 15.8%. The most important laboratory parameters were leucocytosis (16.3±8.2), neutrofilia (14±7.6), sedimentation (41±36) and PCR {26.8±45.4). The etio/ogy was defined in 47.3% of the cases, 21.0% probable and unknown was in 31.5%. In 81.5% of the sputa it was recovered a pathology, in alone blood culture S. was isolated pneumoniae {21.3%), in24% theserologypositive was (22.3% M. pneumoniae and 1.7% C. pneumoniae), H. influenza was isolated in 3 patients, M. tuberculosis in 2 patients, 36.9% of the isolations was associate, M. pneumoniae, H. influenza and S. pneumoniae in 1 O, 5 and 5 patients respective/y.
Conclusions: The etiology of NAC in the studied group doesn't vary of the one reported in other countries, the pneumococo frequency and M. pneumoniae, suggests that the empiric therapies should contemplate these two pathogenies, the resource toasted by the microbiology laboratory allows to define the etiology and the specific treatment.
Article visits 1 | PDF visits 0
Downloads
- Bartlett JG, Dowell SF, Mandell LA, File TM Jr., Musher DM, Fine MJ. Practice Guidelines forthe Management of Community Acquired Pneumonia in Adults. Clinical lnfectious Diseases 2000; 31 :347-382.
- Bartett J.G, Mundy LM. Community-Acquired Pneumonia. The New England Joumal of Medicine 1995; 333:1618-1624.
- World Health Organization. The Wortd health report. 1999: Making a difference. Geneva, World Health Organization 1999; 121.
- Marston B. Epidemiology of Community-Acquired Pneumonia. lnfectious Disease in Clinical Practice 1995; 4(4 Suppl): 8232·8239.
- Morales A. Neumonía Adquirida en la Comunidad. Revista Colombiana de Neumología 1997; 9: 180-182.
- Fang G-D,Fine M, Orloff J, Arisumi D. New and Emerging Etiologies for Community Acquired Pneumonia with lmplications tor Therapy: a prospectiva multicenter study of 359 cases. Medicine 1990; 69:307-16.
- Pautas de la Sociedad Colombiana de Neumología. Diagnóstico y Tratamiento de la Neumonía Adquirida en la Comunidad. Revista Colombiana de Neumología 1995; 7:104-113.
- Smith R.P.C-Reactive Protein, A Clinical Markerin CommunityAcquired Pneumonia. Chest 1995; 108: 1288-91.
- Finch RG, Woodhead MA. Practica! Considerations and Guidelines for the Management of Community-Acquired Pneumonia. Drugs 1998; 55:31-45.
- Chaparro C, Ortega H, Torres C, Giraldo H. Neumonía Adquirida en la Comunidad. Revista Colombiana de Neumología 1989; 1: 19-24.
- Bartlett JG, Ryan KJ, Smith TF, Wilson WR. Laboratory Diagnosis of Lower Respiratory Tract lnfections. Coordinating ed., J.A. Washington 11. Cumitech 7A, Washington D.C. American Society for Microbiology 1987.
- Winn WC. Legionella. En Manual of Clinical Microbiology. P. Murray, EJ. Baron, MA. Pfaller, FC. Tenover, RH. Yolken, editors. Sixth edition. Washington D.C. ASM press 1995; 533-544.
- Vestal AL. Procedures for isolation and identification of mycobacteria. Publication No. (CDC)79-8230. Atlanta. U.S Department of Health and Human Services. Center for Disease Control 1975; 136.
- Sopena N, Sabría M, Pedro-Botet ML. Prospective Study of Community-Acquired Pneumonia of Bacterial Etiology in Adults. Eur. J. Clin Microbiol lnfect Dis 1999; 18:852-858.
- Socan M, Marinie-Fiser N, Kraigher A, Kotnik A, Logar M. Microbial Aetiology of Community-Acquired Pneumonia in Hospitalised Patients. Eur. J Clin Microbio! lnfect Dis 1999; 18:777-782.
- lshida T, Hashimoto T, Arita M, lto 1, Osawa M. Etiology of Community-Acquired Pneumonia in Hospitalized patients: a 3 year prospective study in Japan. Chest 1998; 114:1588-1593.
- Giraldo H, Dueñas A: Neumonías en la Clínica Shaio de Bogotá. Rev. Colomb Neumol 1989; 1: 19-24.
- Morales GA, Rodríguez MM, Cepeda O, Contreras AD. Neumonía Adquirida en la Comunidad. Descripción del perfil de 81 casos hospitalizados durante un periodo de 19 meses en un Hospital General de Bogotá. Rev. Colomb Neumol 1997; 9:180-182.
- Lieberman D, Schlaeffer F, Boldur l. Multiple pathogens in adult patients admitted with Community-Acquired Pneumonia: a one year prospective study of 346 consecutiva patients Thorax 1996; 51:179-184.
- Vergis E.N, Yu VL. New directions for Future Studies of Community-Acquired Pneurnonia: Optimizing lmpact on Patient Care. Eur. J. Clin Microbiol lnfect Dis 1999; 18:847-851.
- Marston BJ, Plouffe JF, File TM. lncidence of Community Acquired Pneumonia requiring hospitalization; results of a population based active surveillance study in Ohio. Archives of Internal Medicine 1997; 157:1709-1718.
- Guglielmo L, Leone R. Aetiology and therapy of CommunityAcquired Pneumonia: a hospital study in northerm ltaly. Eur J. Clin Pharmacology 1997; 51:437-443.
- Marrie T J, Peeling RW, Fine MJ. Ambulatory Patients with Community-Acquired Pneumonia: The frecuency of Atypical Agents and Clinical Course. Am J Med 1996; 101:508-515.
- Trujillo H. Daza C, Robledo J. Neumonía por Mycoplasma pneumoniae en 107 niños de Medellín. Actualizaciones Pediátricas, Fundación Santafé de Bogotá 1998; 8:20-24.
- Trujillo H, Robledo J, Díaz FJ. Etiología y clínica de la IRA baja adquirida en la comunidad en 100 niños estudiados a nivel hospitalario. Medicina UPB 1994; 13:52-64.
- Bohte R, van Furth R, van der Broeck PJ. Aetiology of Community-Acquired Pneumonia: a prospectiva study among adults requiring admission to hospital. Thorax 1995; 50:543-547.
- Gomez J, Sanos V, Gomez JR. Prospectiva study of epidemiology and prognostic factors in Community-Acquired Pneumonia. Eur J Clin Microbiol lnfect Dis 1996; 15:556-560.
- Jaramillo S, García AM, Gonzalez JC, Villegas F, Sierra P. Detección de Chlamydia pneumoniae en placas ateroscleróticas. 11 Encuentro Nacional de Investigación en enfermedades Infecciosas, Resúmenes. lnfectio 2000; 4(1).Resumen C-11.
- Agudelo CI, Diaz PL, Sanabria OM. Vigilancia por el laboratorio de Streptococcus pneumoniae aislado de procesos invasores en población mayor de 5 años, 1998-2001.Informe Quincenal Epidemiológico Quincenal 2002; 7:177-183.