Fisiopatología del asma: una mirada actual
Pathophysiology of asthma: a present-day outlook
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El asma es una enfermedad heterogénea y compleja en constante evolución, ahora hablamos de fenotipos moleculares que van cambiando lentamente su enfoque diagnóstico y terapéutico e identificando nuevos blancos para las herramientas farmacológicas en desarrollo.
Existen factores del huésped que predisponen a los pacientes a desarrollar la enfermedad, factores ambientales y situaciones clínicas que favorecen o agravan el asma.
Se describe la cascada inmunológica con los eventos individuales que llevan al desarrollo del asma y las características de la respuesta inmune en el asma severa además de la remodelación de la vía aérea.
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