Phenotypes of asthma in pediatrics

Fenotipos del asma en Pediatría

Published 2015-07-20

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Vol. 27 No. 3 (2015): Edición Especial: Asma
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Topics review
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Phenotypes of asthma in pediatrics.
rev. colomb. neumol. [Internet]. 2015 Jul. 20 [cited 2024 Nov. 21];27(3). Disponible en: https://doi.org/10.30789/rcneumologia.v27.n3.2015.83
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https://doi.org/10.30789/rcneumologia.v27.n3.2015.83
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Sonia M. Restrepo Gualteros, MD.
Universidad Nacional de Colombia. Universidad El Bosque. Hospital de la Misericordia. Bogotá, Colombia.
    Milena Villamil Osorio, MD.
    Hospital de la Misericordia, Universidad El Bosque. Bogotá, Colombia
      Carlos E. Rodríguez Martínez
      Universidad Nacional de Colombia. Universidad El Bosque. Universidad Militar Nueva Granada. Bogotá, Colombia.
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        Sonia M. Restrepo Gualteros, MD.,

        Neumóloga Pediatra. Universidad Nacional de Colombia. Universidad El Bosque. Hospital de la Misericordia. Bogotá, Colombia.

        Milena Villamil Osorio, MD.,

        Neumóloga Pediatra Hospital de la Misericordia, Universidad El Bosque. Bogotá, Colombia

        Carlos E. Rodríguez Martínez,

        Neumólogo Pediatra, Universidad Nacional de Colombia, Universidad El Bosque, Universidad Militar Nueva Granada. Bogotá, Colombia.
        Knowledge of the existence of various types of wheezing, together with their distinctive characteristics, gives a view of the development of asthma and its natural history. Asthma is a complex disease with multiple pathophysiological mechanisms. Identification of these  henotypes is important for the study of the developmental pathways of asthma and the underlying mechanisms of the disease, in order to better decide what the most adequate therapy is and to predict the clinical evolution of these patients. The purpose of this review is to describe the studies available in the literature, in order to approach and describe the phenotypes of wheezing in childhood and their risk factors.

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        1. Von Mutius E. Trajectories of childhood wheeze. J Allergy Clin Immunol. 2011;127:1513-4.
        2. Hultz A, Brand PL. Episodic viral wheeze and multiple trigger wheeze in preschool children: a useful distinction for clinicians?Paediatr Respir Rev. 2011;12:160-4.
        3. Martínez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med. 1995;332(3):133-8.
        4. Stein RT, Holberg CJ, Morgan WJ, Wright AL, Lombardi E, Taussig L, Martinez FD. Peak flow variability, methacholine responsiveness and atopy asmarkers for detecting different wheezing phenotypes in childhood. Thorax. 1997;52:946-52.
        5. Kurukulaaratchy RJ, Fenn M, Matthews S, Arshad SH. Characterization of atopic and non-atopic wheeze in 10 year old children. Thorax. 2004;59:563-8.
        6. Lau S, Illi S, Sommerfeld C, Niggemann B, Volkel K, Madloch C, Gruber C, et al. Transient early wheeze is not associated with impaired lung function in 7-yr-old children. Eur Respir J. 2003;21:834-41.
        7. Matricardi PM, Illi S, Gruber C, et al. Wheezing in childhood: incidence, longitudinal patterns and factors predicting persistence. Eur Respir J. 2008;32:585-92.
        8. Savenije OE, Granell R, Caudri D, Koppelman GH, Smit HA, Wijga A, et al. Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA. J Allergy Clin Immunol. 2011;127:1505-12.e14.
        9. Bhatt JM, Smyth AR. The management of preschool wheeze. Paediatr Respir Rev. 2011;12:70-7.
        10. Brand PL, Baraldi E, Bisgaard H, et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J. 2008; 32:1096-110.
        11. Brand PL, Caudri D, Eber E, Gaillard EA, Garcia-Marcos L, Hedlin G, et al. Classification and pharmacological treatment of preschool wheezing: changes since 2008. Eur Respir J.2014;43:1172-7.
        12. Lodge CJ, Lowe AJ, Allen KJ, Zloumis S, Gurrin LC, Matheson MC, et al. Childhood wheeze phenotypes show less than expected growth in FEV1 across adolescence. Am J Respir Crit Care Med. 2014;89:1351-8.
        13. Castro-Rodríguez JA. A new childhood asthma phenotype: obese with early menarche. Paediatric Respiratory Reviews. 2016;18:85-9.
        14. Wenzel SE. Complex phenotypes in asthma: Current definitions. Pulmonary Pharmacology & Therapeutics 2013;26:7105.
        15. Wahn U, Matricardi P. Toward a definition of asthma phenotypes in childhood: Making a long way shorter? J Allergy Clin Immunol 2012;130:111-2.
        16. Tenero L, Piazza M, Piacentini G. Recurrent wheezing in children. Transl Pediatr 2016;5(1):31-6.
        17. Gilmour MI, Jaakkola MS, London SJ, Nel AE, Rogers CA. How exposure to environmental tobacco smoke, outdoor air pollutants, and increased pollen burdens influences the incidence of asthma. Environ Health Perspect. 2006;114: 627-33.
        18. Reddy M, and Covar R. Asthma phenotypes in childhood. Curr Opin Allergy Clin Immunol. 2016;16(2):127-34.
        19. Diamant Z, Hanania N. The new look on asthma: linking phenotypes, endotypes and biomarkers to asthma management. Curr Opin Pulm Med. 2015;21:1-2.
        20. Aspectos particulares del tratamiento de asma en niños. Capítulo 41. En: García, Caraballo. Asma: Enfoque integral y nuevas tendencias. Segunda Edición. Ed Médica Panamericana2014.

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