Clinical use of pulmonary function tests and high-resolution tomography in interstitial lung diseases
Uso clínico de las pruebas de función pulmonar y la tomografía de alta resolución en las enfermedades pulmonares intersticiales
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Diagnosis of interstitial lung diseases is generally arrived at by clinical history, physical examination, and radiologic images, especially high-resolution CT-scanning.
It is important to note that, while these diseases have different clinical and histological characteristics, they share a
basic pattern of abnormal lung function. With regard to high-resolution tomography, the characteristics of these diseases
are similar, although there are specific differences that can be helpful for correct diagnosis.
These diseases have severe consequences on respiratory gas exchange. These alterations, combined with other abnormalities of lung function, cause the signs and symptoms and have an impact on quality of life.
The use of physiologic parameters is not only helpful for diagnosis, but can also assess severity, help to define the consequences of treatment, and aid in the follow-up. Although some pulmonary function tests can remain completely normal with severe radiographic findings, 10% of patients have impaired lung function before radiologic changes (1).
High-resolution tomography is an essential imaging tool for the study of these patients. This is true not only for diagnosis, but also with regard to clinical parameters and follow-up. Its prognostic use is continually gaining importance.
In this article we assess the clinical use of pulmonary function tests and high-resolution tomography in interstitial lung diseases.
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