Primary Mediastinal Small Cell Carcinoma
Carcinoma mediastinal de célula pequeña primario
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A mediastinal small cell neuroendocrine carcinoma is a rare form of malignancy. Diagnosis requires imaging studies, pathological identification and immunohistochemistry markers. These tumors are aggressive and recurrence and metastases frequently complicate patient management. We present a case 78-year-old woman with complaints over 4 months of weight loss of four kilograms, cough and expectoration. Normal chest physical examination. History of smoking twenty pack-years. Chest X-ray showed a soft tissue density in the right border in region cardiomediastinun region. A computed tomography scan showed an infiltrative soft tissue in the right upper and middle mediastinum diameter of 4.9 x 4.7 x 7.4 centimeters involving major bronchovascular structures. The biopsy was performed by video thoracoscopy. Histologic analysis of the biopsies and inmunohistoquimical studies were positive for different markers and concluded small cell neuroendocrine carcinoma.
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