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Cardiopulmonary optimization and quality of life in the recovery phase of COVID-19 infection through a rehabilitation program

Optimización cardiopulmonar y de la calidad de vida en la fase de recuperación de la infección por COVID-19 a través de un programa de rehabilitación




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Research article

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Cardiopulmonary optimization and quality of life in the recovery phase of COVID-19 infection through a rehabilitation program.
rev. colomb. neumol. [Internet]. 2022 Nov. 30 [cited 2024 Dec. 4];34(2):17-24. Disponible en: https://doi.org/10.30789/rcneumologia.v34.n2.2022.574

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Juan Sebastián Theran León MD
    Álvaro Luis Ruge Serrano MD
      Rafael Guillermo Parales Strauch MD
        Nelson Darío Gómez Lozada MD

          Introduction: COVID-19 disease can cause a wide variety of long-term health problems, such as impaired lung function, reduced exercise performance, and decreased quality of life. Our study aimed to investigate the efficacy, feasibility, and safety of pulmonary rehabilitation in patients with COVID-19 and to compare the results between patients with a mild/moderate and severe/critical course of the disease.

          Materials and Methods: Patients in the post-acute phase of a mild to critical course of COVID-19 admitted to a comprehensive pulmonary rehabilitation program were included in this prospective, observational cohort study. Various measures of exercise performance, 6-minute walk distance, lung function (forced vital capacity (FVC)), and quality of life (36-question short-form health survey (SF-36)) were assessed before and after. We include 43 patients in this study (20 with mild/moderate COVID and 23 with severe/critical COVID-19).

          Results: At admission, patients had reduced walking distance (mild: median 401 m, interquartile range (IQR) 335-467 m; severe: 108 m, 84-132 m), impaired FVC (mild: 72%, severe: 35%,) and a low SF-36 mental health score (mild: 52 points, severe: 32 points). This patients received sessions adjusted to their physical abilities, and in both subgroups the patients improved on the walking test of 6 min (mild/moderate: +54m, severe/critical: +117m, both p < 0.002), FVC (mild/moderate: +8.9%, p=0.004; severe/critical: +12.4%, p <0.003) and mental component SF-36 (mild / moderate: +6.8 points, p = 0.062; severe / critical: +16.7 points, -p <0.005).

          Discussion and Conclusions: A well-structured exercise program results in a benefit in the patients’ spheres of aerobic capacity, lung volumes and quality of life, in this sense it is recommended to expand population samples to be able to apply our protocol to other centers in charge of  the rehabilitation of COVID 19 patients.


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