The alveolar-capillary membrane

La membrana alveolo-capilar

Published 2016-08-07

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Vol. 26 No. 3 (2014)
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Research article
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The alveolar-capillary membrane.
rev. colomb. neumol. [Internet]. 2016 Aug. 7 [cited 2024 Nov. 24];26(3). Disponible en: https://doi.org/10.30789/rcneumologia.v26.n3.2014.38
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Carmelo Dueñas Castell, MD.
Universidad de Cartagena. UCI Gestión Salud, UCI Santa Cruz de Bocagrande. Cartagena, Colombia.
    Adriana Fortich Salvador, MD.
    Departamento de Medicina Interna, Universidad de Cartagena. Cartagena, Colombia.
      Guillermo Ortiz Ruiz, MD.
      Universidad El Bosque. Hospital Santa Clara. Bogotá, Colombia.
        Show authors biography

        Carmelo Dueñas Castell, MD.,

        Profesor Universidad de Cartagena. Intensivista UCI Gestión Salud, UCI Santa Cruz de Bocagrande. Cartagena, Colombia.

        Adriana Fortich Salvador, MD.,

        Residente III de Medicina Interna, Universidad de Cartagena. Cartagena, Colombia.

        Guillermo Ortiz Ruiz, MD.,

        Jefe postgrado de Medicina Interna, Universidad El Bosque. Jefe UCI Hospital Santa Clara. Profesor Universidad El Bosque. Bogotá, Colombia.

        The alveolar-capillary membrane has been the subject of multiple studies. Knowledge of its vital role in gas exchange and in immune modulation in various clinical settings has increased greatly in recent times. We review the most important aspects of current scientific knowledge about the alveolar-capillary membrane and its role in conditions such as the acute respiratory distress syndrome and ventilator-induced lung injury. Current evidence about the role of various cells and humoral mediators in the pathophysiology of the alveolar-capillary membrane is also summarized. Understanding the available literature on the immunomodulating function of the alveolar-capillary membrane, and its interaction with cells, immune products, receptors, channels, and ways of expression, should facilitate knowledge of the pathophysiological aspects of the alveolar-capillary membrane. This, in its turn, should improve the management of critically ill patients and have an impact on vital clinical outcomes.

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