Pulmonary paracoccidioidomycosis. Report of two cases
Paracoccidioidomicosis pulmonar. Reporte de dos casos
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Paracoccidioidomycosis, or South American blastomycosis, is a systemic, progressive, and chronic fungal disease, caused by Paracoccidioides brasiliensis. This disease is to be found only in Latin America, and is a relevant public health concern.
We expose two clinical cases, both of male adult farmers who presented with hemoptysis and abnormal weight loss. Radiographs showed nodular patterns, and computed tomographies of the chest showed ground-glass opacities and cavitary nodules. In both cases, bronchoscopy with bronchoalveolar lavage was carried out, plus Gomori histochemical stain that showed large and small spherical mycotic yeasts, with characteristic “ship’s wheel” formations, consistent with paracoccidioidomycosis.
Epidemiological factors, together with a complete clinical history and radiological findings, plus bronchoscopy with consistent histochemistry, lead to diagnosis and confirmation of pulmonary paracoccidioidomycosis, which allows for timely and adequate management, with the aim of preventing significant sequelae.
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- Torrado E, Castañeda E, De la Hoz F, Restrepo A. Paracoccidioidomicosis: Definición de las áreas endémicas de Colombia. Biomédica. 2000;20(2):327-34.
- Wanke B, Abidon M. Paracoccidioidomycosis. J Bras Pneumol. 2009;35:1245-49.
- Bagagli E, Theodoro RC, Bosco SM, McEwen JG. Paracoccidioides brasiliensis: phylogenetic and ecological aspects. Mycopathologia. 2008;165:197-207.
- Costa AN, Benard G, Pereira AL, Fujita CL, Kono AS, Salge JM, et al. The lung in paracoccidioidomycosis: new insights into old problems. Clinical Science. 2013;68(4):441-48.
- Bocca AL, Amaral AC, Teixeira MM, Sato PK, ShikanaiYasuda MA, Soares Felipe MS. Paracoccidioidomycosis: eco-epidemiology, taxonomy and clinical and therapeutic issues. Future Microbiol. 2013;8(9):1177-91.
- Bennett J, Dolin R, Blaser M. Principles and practice of infectious diseases. 8th. Edition. 2014:2996-8.
- Barreto MM, Marchiori E, Amorim VB, Zanetti G, Takayassu TC, Escuissato DL, et al. Thoracic paracoccidioidomycosis: Radiographic and CT Findings. RadioGraphics. 2012;32:71-84.
- Costa de Freitas RM, Prado R, Silva do Prado FL, Braga de Paula I, Alves Figueiredo MT, Ferreira CS, et al. Pulmonary paracoccidiodomycosis: radiology and clinical-epidemiological evaluation. Revista do Sociedade Brasileira de Medicina Tropical. 2010;43(6):651-56.
- Marchiori E, Valiante PM, Mauro Mano P, Zanetti G, Escuissato DL, Souza AS, et al. Paracoccidioidomycosis: High-resolution computed tomography - pathologic correlation. Eur J Radiol. 2011;77:80-4.
- Arciniegas Quiroga W, Orjuela Zuluaga DL. Paracoccidioidomicosis crónica. Reporte de un caso. Investigaciones Andina. 2011;22(13):228-35.
- Shikanai Yasuda MA. Paracoccidioidomycosis treatment. Rev Inst Med Trop. Sao Paulo. 2015;57(19):31-7.
- Mendez-Lemaitre A. Blastomicosis suramericana y otras micosis en Colombia. Rev Hosp Samaritana. 1950;1:3-20.
- Moriones Robayo CA, Guerra Ortiz CP. Histoplasmosis laríngea: reporte de primer caso en Colombia. Colombia Médica. 2014;45(4).
- Torrado E, Castañeda E, de la Hoz H, Restrepo A. Paracoccidioidomicosis: definición de las áreas endémicas de Colombia. Biomédica. 2000:20:327-34.
- Restrepo A, Salazar ME, Cano LE, Stover P, Feldaman D, Stevensa DA. Estrogens inhibit mycelium to yeast transformation in the fungus Paracoccidioides brasiliensis. Infect Immunol.1984;46:346-53.
- Travassos LR, Taborda CP. Paracoccidioidomycosis vaccine. Human Vaccines & Immunotherapeutics. 2012;8.
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