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Lymphocytic interstitial pneumonia associated with systemic lupus erythematosus. An uncommon, but not inexistent condition

Neumonía intersticial linfocítica asociada a lupus eritematoso sistémico. Una neumopatía infrecuente pero no inexistente




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Lymphocytic interstitial pneumonia associated with systemic lupus erythematosus. An uncommon, but not inexistent condition.
rev. colomb. neumol. [Internet]. 2016 Mar. 30 [cited 2024 Nov. 21];28(1):39-44. Disponible en: https://doi.org/10.30789/rcneumologia.v28.n1.2016.163

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Martha Alejandra Casallas Rivera, MD.
    Alejandro González Muñoz, MD.
      María José Ospina Perdomo, MD.

        Martha Alejandra Casallas Rivera, MD.,

        Médico internista. Servicio de Medicina Interna, Hospital Universitario de La Samaritana. Residente de Medicina Interna. Universidad de La Sabana. Bogotá, Colombia.


        Alejandro González Muñoz, MD.,

        Médico internista. Servicio de Medicina Interna, Hospital Universitario de La Samaritana. Estudiante de Medicina. Pontificia Universidad Javeriana. Bogotá, Colombia.


        María José Ospina Perdomo, MD.,

        Médico internista. Servicio de Medicina Interna, Hospital Universitario de La Samaritana. Residente de Medicina Interna. Universidad de La Sabana. Bogotá, Colombia.


        Lymphocytic interstitial pneumonia is an uncommon condition characterized by non-neoplastic lymphoid hyperplasia of the interstitial lymphoid tissue of the lung. It is associated with autoimmune phenomena or viral infections, human immunodeficiency virus or mononucleosis, as well as systemic lupus erythematosus, although it is uncommon. The symptoms vary: dry cough, chest pain, dyspnea, and, less often, fever, arthralgia, and weight loss.

        We present the case of a 40-year old female with a background of systemic lupus erythematosus diagnosed in 1998, who presented with pulmonary illness consistent with lymphocytic interstitial pneumonia, confirmed by clinical, radiologic, and histopathologic findings. She was treated with corticoids, cyclophosphamide, azathioprine, and immunoglobulin; however, due to her compromised immunologic system, she has developed several infectious complications.


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