Factores de riesgo para recaída de tuberculosis pulmonar en pacientes del Hospital Santa Clara de Bogotá 1992/2000
Factores de riesgo para recaída de tuberculosis pulmonar en pacientes del Hospital Santa Clara de Bogotá 1992/2000
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Pulmonary tuberculosis relapse is defined as these patients that make recurrence of tuberculosis after complete an adequate treatment, and these patients are again diagnosed bacteriologically with tuberculosis. We tried to identify the risk factors for relapse among adults, through an analitical study of cases and controls, with eighty patients among the tuberculosis programme of Santa Clara Hospital between 1992-2000 with relapse diagnosis which meet criterion of case and eighty patients which meet criterion of control. We did a bivariate analysis with confidence intervals and univariate calculation with logistic regression analysis to predict the development of relapse for the different variables.
Results : We found that the next variables are joined with relapse, alcoholism with OR 2.6 IC 1.063-6.42, addicted to smoking OR 2.2 IC 1.066-6.457, extrapulmonary compromise OR 2.4 IC 1.7-2.4, two or more lobules compromised OR 8.5 IC 3.9-18, pleural thickened OR 3.1 IC 1.3-7.4, fibrothorax OR 10 IC 2.3-47.2.
Diabetes mellitus, chronic renal failure, silicosis are associated with relapse, but in our study we found another facotrs which are joined to relapse and we suggest that if we find these factors among tuberculosis patients would indicate the chance of relapse and this would create the necessity of use a larger number of doses of antituberculosis medicaments.
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