Asma. Tres fenotipos en el asma de inicio en el adulto por medio de algoritmos de agrupamiento (clusters)

Asthma. Three phenotypes in adult-onset asthma determined by clustering algorithms

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Gustavo Adolfo Hincapié Díaz, MD.

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Biografía del autor/a (VER)

Gustavo Adolfo Hincapié Díaz, MD., Hospital Militar Central. Universidad Militar Nueva Granada. Bogotá, Colombia.

Internista, Neumólogo, Hospital Militar Central. Universidad Militar Nueva Granada. Bogotá, Colombia.

Referencias (VER)

Moore WC, Meyers DA, Wenzel SE, et al. Identification of asthma phenotypes using cluster analysis in the severe asthma research program. Am J Respir Crit Care Med. 2010;181:315-323.

Siroux V, Basagana X, Boudier A, Pin I, Garcia-Aymerich J, Vesin A, et al. Identifying adult asthma phenotypes using a clustering approach. Eur Respir J. 2011;38:310-317.

Haldar P, Pavord ID, Shaw DE, Berry MA, Thomas M, Brightling CE, et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med. 2008;178:218-224.

Ten Brinke A, van Dissel JT, Sterk PJ, Zwinderman AH, Rabe KF, Bel EH. Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection. J Allergy Clin Immunol 2001;107:449-454.

Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet. 2012;380:651-659.

Sutherland ER, Lehman EB, Teodorescu M, Wechsler ME. Body mass index and phenotype in subjects with mild-to-moderate persistent asthma. J Allergy Clin Immunol. 2009;123:1328-1334.

Ronmark E, Lindberg A, Watson L, Lundback B. Outcome and severity of adult onset asthma–report from the obstructive lung disease in northern Sweden studies (OLIN). Respir Med. 2007;101:2370-2377.

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