Nódulos pulmonares subsólidos: presentación de casos y estado actual

Juan Carlos Varón Cotes, MD., Luis Gerardo García Herreros, MD.

Resumen


El avance reciente en la tecnología escanográfica con la introducción de tomografía axial con multidetectores, ha permitido diferenciar, cada vez con mayor asiduidad, la presencia de lesiones pulmonares denominadas nódulos pulmonares subsólidos u opacidades nodulares en vidrio esmerilado, las cuales pueden asociarse con diferentes etiologlas, incluso con cáncer pulmonar. Aún no hay consenso acerca de cómo abordar, dar seguimiento, diagnosticar o tratar dichas lesiones, y por ello con este artículo se pretende revisar su estado actual a propósito de cuatro casos clínicos tratados en la Fundación Santa Fe de Bogotá.


Palabras clave


nódulo subsólido; vidrio esmerilado; adenocarcinoma; adenocarcinoma in situ; hiperplasia adenomatoide atípica

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Referencias


Hansell DM. Bankier AA. MacMahon H. et al. Fleischner society: glossary of terms for thoracic imaging Radlology. 2008; 246: 697-722.

Suzuki K, Kusumoto M, Watanabe S, et al. Radiologic classification of small adenocarcinoma of the lung: radiologic-pathologic correlation and its prognostic impact. Ann Thorac Surg. 2006; 81: 413-9.

Kaneda H. Sakaida N, Saito T. et al. Appearance of bronchioloalveolar carcinoma and the rapid progression into invasive papillary adenocarcinoma. Gen Thorac Cardiovasc Surg. 2009; 57: 224-7.

Libby DM, Wu N, Lee IJ, et al. CT screening for fung cancer: the value of short-term CT follow-up. Chest. 2006; 129: 1039-42.

Park CM, Goo JM, Lee HJ, Lee CH, Chun EJ, Jm JG. Nodular ground-glass opacity at thin-section CT: histoloqic correlation and evaluation of change at follow-up. Radiographics. 2007; 27: 391-408.

Detterbeck F, Homer R. Approach to the ground-glass nodule. Clin Chest Med. 2011, 32: 799-810.

Kim H, Chot Y, Kim K, et al. Management of ground glass opacity lesions detected In patients with other wise operable nonsmall cell lung cancer. J Thorac Oncol. 2009; 4: 1242-6.

Lindell RM, Hartman TE, Swensen SJ, et al 5-year lung cancer screening experíence. Chest. 2009; 136: 1586-95.

Hasegawa M, Sone S, Takashlma S. et al. Growthrate of small lung cancers detected on mass CT screening. Br J Radiol. 2000; 73: 1252-9.

Hiramatsu M, lnagaki T, lnagaki T, et al. Pulmonary ground-glass opacity (GGO) lesions-large size and a history of lung cancer are risk factors for growth. J Thorac Oncol. 2008, 3: 1245-50.

Kakinuma R. Ohmatsu H. Kaneko M, et al. Progression of focal pure ground-glass opacity detected by low dose hellcal computed tomography screening for lung cancer. J Comput Assist Tomogr. 2004; 28: 17-23.

Min JH, Lee HY. Lee KS, et al. Stepwise evolution from a focal pure pulmonary ground-glass opacity nodule into an invasive lung adenocarcinoma: an observation for more than 1 O years. Lung Cancer. 201 O; 69: 123-6.

Jennings SG, Winer-Muram HT, Tarver RO, et al. Lung tumor growth: assessment with CT-<:omparison of diameter and crosssectional area with volume measurements. Radiology. 2004; 231: 866-71.

Oda S, Awai K, Murao K, et al. Computer-aided volumetry of pulmonary nodules exhibiting ground-glass opacity al MDCT AJR Am J Roentgenol. 2010; 194: 398-406.

Nomori H, Watanabe K, Ohtsuka T, et al. Evaluation of F-18 fluorodeoxyglucose (FDG) PET scanning for pulmonary nodules less than 3 cm in diameter, with special reference to the CT images. Lung Cancer. 2004: 45: 19-27.

Shimizu K, lkeda N, Tsuboi M, et al. Percutaneous CT-guided fine needle aspiration for lung cancer smaller than 2 cm and revealed by ground-glass opacity al CT. Lung Cancer. 2006; 51: 173-9.

Hur J, Lee HJ, Nam JE, et al. Diagnostic accuracy of CT fluoroscopy-guided needle aspiration biopsy of ground-glass opacity pulmonary lesions. AJR Am J Roentgenol. 2009; 192: 629-34.

Sortini D, Feo C, Maravegias K, et al. lntrathoracoscopic localization techniques. Surg Endose. 2006; 20: 1341-7.

Daniel T, Altas T, Rehm P, et al. A novel technique for localization and excisional biopsy of small or llldefined pulmonary lesions. Ann Thorac Surg. 2004; 77: 1756-62 [discussion: 1762].

Travis WD. Brambilla E, Noguchi M. et al. lnternational Association for the Study of Lung Cancer/ American Thoracic Society/ European Respiratory Society lnternational Multidisciplinary Classification. of Lung Adenocarcinoma. J Thorac Oncol. 2011; 6.

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Non Small cell Lung cancer. Version 2. 2012. Disponible en: www.nccn.org.

Yoshida J, lshii G, Yokose T, et al. Possible delayed cut-end recurrence after llmíted resection for ground-glass opacity adenocarcinoma, lntraoperatively diagnosed as Noguchi type 8, in three patients. J Thorac Oncol. 2010; 5: 546-50

Kim T J, Goo JM, Lee KW, et al. Clinical, pathological and thinsection CT features of persisten! multiple ground-glass opacity nodules: comparison with solitary ground-glass opacity nodule. Lung Cancer. 2009; 64: 171-8.




DOI: http://dx.doi.org/10.30789/rcneumologia.v24.n2.2012.185

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